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RNA Structure Prediction Online Exam Quiz

Important questions about RNA Structure Prediction. RNA Structure Prediction MCQ questions with answers. RNA Structure Prediction exam questions and answers for students and interviews.

RNA structures can be experimentally determined using _____

Options

A : a. X-ray crystallography techniques only

B : b. NMR techniques only

C : c. X-ray crystallography or NMR techniques

D : d. Gel electrophoresis

Which of the following is not a form of RNA?

Options

A : a. mRNA

B : b. tRNA

C : c. qRNA

D : d. rRNA

Unlike DNA, which is mainly double stranded, RNA is double stranded, although an RNA molecule can self-hybridize at certain regions to form partial double-stranded structures.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

Structures are not much important when it comes to the study of the functions.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

Which of the following is not a base of RNA?

Options

A : a. Thymine (T)

B : b. Adenine (A)

C : c. Cytosine (C)

D : d. Guanine (G)

Base pairing, in RNA, is A–G and U–C.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

In addition to the canonical base pairing, there often exists non-canonical base pairing such as _________ and ________ base paring.

Options

A : a. G, U

B : b. G, C

C : c. U, C

D : d. A, C

Four main subtypes of secondary structures can be identified. They are hairpin loops, bulge loops, interior loops, and multi-branch loops.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

The ______ refers to a structure with two ends of a single-stranded region (loop) connecting a base-paired region (stem).

Options

A : a. helical junctions

B : b. hairpin loop

C : c. bulge loop

D : d. interior loop

The __________ refers to two single-stranded regions on opposite strands connecting two adjacent base-paired segments.

Options

A : a. hairpin loop

B : b. interior loop

C : c. pseudoknot loop

D : d. helical junctions

At present, there are essentially two types of method of RNA structure prediction. One is the minimum free energy approach and the Second one is a comparative approach.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

Ab initio approach makes structural predictions based on ______

Options

A : a. a single RNA sequence

B : b. comparing RNA sequences

C : c. evolutionary basis

D : d. pure phylogenetics

In ab initio approach, generally, when a base pairing is formed, the energy of the molecule is _________ because of attractive interactions between the two strands.

Options

A : a. lowered

B : b. increased

C : c. multiplied

D : d. kept stable

In ab initio methods, free energy can be calculated based on parameters empirically derived for small molecules.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

The energy necessary to form individual base pairs is not quite affected by adjacent base pairs.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

The attractive interactions lead to _________ energy.

Options

A : a. increased

B : b. higher

C : c. lower

D : d. no change in

If the base pair is adjacent to loops or bulges, the neighboring loops and bulges tend to ___________ the base-pair formation.

Options

A : a. have no change on

B : b. decrease the energy

C : c. stabilize

D : d. destabilize

The scoring scheme based on the combined stabilizing and destabilizing interactions forms the foundation of the ab initio RNA secondary structure prediction method.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

Ab initio methods are energetically least favorable.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

The dot matrix method and the dynamic programming method can be used in detecting self-complementary regions of a sequence.

Options

A : a. True

B : b. False

C : c. May be True or False

D : d. Can't say

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