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Antibody Online Exam Quiz

Important questions about Antibody. Antibody MCQ questions with answers. Antibody exam questions and answers for students and interviews.

1. Which of the following mediates Type I hypersensitivity reaction?

Options

A : IgE

B : IgG

C : IgM

D : IgD

2. The class of immunoglobulin, most abundant in body is

Options

A : IgD

B : IgE

C : IgG

D : IgM

3. Anti-Rh antibodies are

Options

A : IgG type

B : IgA type

C : IgE type

D : IgD type

4. Simulation of which of the following will lead to appearance of first antibody to appear following stimulation by an antigen?

Options

A : IgM

B : IgA

C : IgE

D : IgG

5. Which of the following is the phylogenetically oldest immunoglobulin?

Options

A : IgE

B : IgM

C : IgG

D : All are similar

6. The secretary component of sIgA is

Options

A : made by plasma cells that secrete dimeric IgA

B : added to dimeric IgA by the M cell

C : formed by cleavage of an epithelial cell receptor used to transport the dimeric IgA across the epithelial cell

D : made by T cells

1. The class of immunoglobulins which can cross the placenta is

Options

A : IgM

B : IgG

C : IgA

D : IgD

2. Heat-labile class of immunoglobulins include

Options

A : IgA

B : IgE

C : IgG

D : IgM

3. Which of the following (s) is/are function (s) of Fc fragment of IgG?

Options

A : It determines catabolic rate

B : It binds complement

C : It is related to passage of IgG across the placental barrier

D : All of these

4. J chain is present in

Options

A : IgA

B : IgM

C : Both (a) and (b)

D : IgE

5. Which is the most efficient complement fixing class of antibody?

Options

A : IgE

B : IgA

C : IgM

D : IgG

6. Which is not a function of IgG?

Options

A : Major antibody in serum

B : First antibody type produced against an antigen during the primary antibody response

C : Activates or fixes complement

D : Involved in opsonization

7. Self reactive antibodies are not found in significant concentration in normal serum because

Options

A : it is impossible to generate a self-reactive antibody

B : self reactive B cells are killed by CD8 T cells

C : B cells that are stimulated via their surface bound antibody in the absence of T cell help to commit suicide

D : self reactive B cells switch to IgA which is all secreted and not present in serum

8. Antigen binding sites of an immunoglobulin are located in

Options

A : light chain alone

B : heavy chain alone

C : F c region of the antibody

D : Fab regions of the antibody

9. Which of the following theory of antibody production is most widely accepted?

Options

A : Side chain theory

B : Clonal selection theory

C : Direct template theory

D : Indirect template theory

10. Which is not a function of IgA?

Options

A : Protect mucosal surfaces

B : Fix complement

C : Protect eyes

D : Agglutinate antigen

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