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Antibiotics Online Exam Quiz

Important questions about Antibiotics. Antibiotics MCQ questions with answers. Antibiotics exam questions and answers for students and interviews.

1. Penicillin is produced by

Options

A : aerobic fermentation

B : anaerobic fermentation

C : aerobic fermentation followed by anaerobic fermentation

D : anaerobic fermentation followed by aerobic fermentation

2. Penicillin is recovered after fermentation as

Options

A : potassium penicillin

B : calcium penicillin

C : sodium penicillin

D : penicillin only

3. Streptomycin is produced by

Options

A : S. griseus

B : S. griseoflavus

C : S. aerofaciens

D : S. ramosus

4. Which of the following organism(s) produce(s) tetracycline?

Options

A : Steptomyces aureofaciens

B : Steptomyces ramosus

C : Nocardia sulphurea

D : All of these

5. Which of the following changes occur during first phase of growth of Penicillium chrysogenum ?

Options

A : Growth of mycelia occurs

B : Ammonia is liberated in the medium

C : Lactic acid present in the corn steep liquor is utilized at the maximum rate

D : All of the above

6. At acidic pH, penicillin remains in

Options

A : aqueous phase

B : solvent phase

C : both (a) and (b)

D : precipitates

7. Inoculum preparation for the fermentation medium for penicillin takes place on

Options

A : wheat seeds

B : barley seeds

C : rice seeds

D : all of these

8. High yield of chlorotetracyclin requires

Options

A : no aeration

B : continuous aeration

C : aeration which does not affect the yield

D : controlled aeration

9. Which of the following event occurs during third phase of growth of P chrysogenum ?

Options

A : Concentration of antibiotic increases in the medium

B : Autolysis of the medium starts

C : Slight rise in pH due to liberation of ammonia

D : All of the above

10. Which of the following event occurs during second phase of growth of P. chrysogenum ?

Options

A : Synthesis of penicillin is high

B : Mycelial mass increases

C : pH increase

D : Both (a) and (b)

1. Vegetable oil, (corn oil or soybean oil) added in the fermentation medium for penicillin, act as

Options

A : source of nutrients

B : carbon source

C : antifoam agent

D : both (a) and (c)

1. At normal pH, penicillin remains in

Options

A : aqueous phase

B : solvent phase

C : both (a) and (b)

D : precipitates

2. Fermentation medium for oxytetracyclin (terramycin) consist of

Options

A : CSL, starch, (NH 4 ) 2 SO 4 , sodium chloride and CaCO 3

B : CSL, (NH 4 ) 2 SO 4 , sodium chloride and CaCO 3

C : CSL, starch,(NH 4 ) 2 SO 4 , ammonium chloride and CaCO 3

D : CSL,(NH 4 ) 2 SO 4 , ammonium chloride and CaCO 3

3. Which of the following precursor is added in the medium to get penicillin G?

Options

A : Phenyl carbamic acid

B : Phenyl acetic acid

C : Ammonium sulphate

D : Ammonium chloride

4. Antibiotics are typically produced in fed batch reactors because

Options

A : antibiotic yields are generally higher when cells enter the stationary phase

B : the precursors are often toxic to the cells

C : antibiotic yields are generally higher when cell growth slows

D : All of the above

5. Media composition for the production of streptomycin is

Options

A : soybean meal, glucose, peptone, malt extract, sodium chloride

B : soybean meal, glucose, peptone, malt extract, ammonium chloride

C : soybean meal, glucose, peptone, malt extract, calcium carbonate

D : soybean meal, glucose, peptone, malt extract, ammonium sulphate

6. The yield of the antibiotic depends upon

Options

A : pH of the medium

B : age of the inoculum

C : composition of the medium

D : all of these

7. Chlorotetracyclin is soluble in

Options

A : organic solvents

B : water

C : ether

D : all of these

8. During which phase of growth of Penicillium chrysogenum maximum antibiotic production takes place

Options

A : during the first phase

B : during the second phase

C : during the third phase

D : same in all the phases

9. pH of the fermentation medium for chlorotetracyclins is

Options

A : 5-6

B : 6-7

C : 7-8

D : 8-9

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